Restylane Defyne with Lidocaine (1 × 1 mL) is a hyaluronic acid dermal filler designed for the correction of deep facial wrinkles and folds while maintaining natural facial movement and expression.
It is commonly used for treating nasolabial folds, marionette lines, and other dynamic areas of the face that require flexibility combined with reliable structural support.
The formulation is based on XpresHAn Technology™, allowing the gel to adapt to facial dynamics and provide balanced correction without stiffness.
Lidocaine is included to enhance patient comfort during injection and support precise, controlled placement.
Rheological properties / Product data
HA concentration: 20 mg/ml
Technology: XpresHAn Technology™
Elasticity (G’): Medium–high
Cohesivity: Medium
Texture: Flexible, resilient HA gel
Lidocaine content: 0.3%
Packaging: 1 syringe × 1 ml
Injection depth & tools
Recommended depth: Mid to deep dermis
Injection techniques: Linear threading, fanning
Recommended instruments: Needle or cannula depending on indication
Storage & handling
Store at room temperature (do not freeze)
Protect from direct sunlight
Single-use only — use immediately after opening
Do not use if packaging is damaged or expired
Dispose of syringes and needles according to medical waste regulations
For use by licensed medical professionals only. Not intended for self-injection.
Technique, plane and volume selected by clinician based on indication; aspirate and inject slowly.
Common: redness, swelling, bruising, tenderness. Rare but serious: vascular occlusion (blanching, severe pain, visual changes—urgent care required).
Cross‑linked HA restores volume and contour; integrates with surrounding tissue.
Avoid alcohol 24h before and after treatment—vasodilation increases bleeding/bruising and may slow recovery.
Not recommended in pregnancy—elective injectables lack robust safety data; defer until after delivery.
Not advised during breastfeeding—limited data on transfer via milk and infant safety; postpone elective procedures.
