Restylane Kysse with Lidocaine is an innovative hyaluronic acid filler formulated for lip enhancement, fine line correction, and natural definition of the perioral area. Its Optimal Balance Technology™ (OBT) ensures a soft, flexible gel that moves naturally with facial expressions while maintaining long-lasting volume and hydration.
With a hyaluronic acid concentration of 20 mg/ml and 0.3 % lidocaine, the product offers a perfect balance between structure and elasticity - ideal for subtle lip augmentation, border definition, and corner lift. The smooth monophasic gel integrates evenly into tissue, providing soft palpation and a natural look, while minimizing swelling and recovery time.
Clinical results typically last 6-12 months, depending on the patient's metabolism, technique, and treatment area.
Rheological properties / Product data
HA concentration: 20 mg/ml
Cross-linking agent: BDDE
Elasticity (G′): Medium
Cohesivity: High
Texture: Monophasic, smooth, cohesive gel
Lidocaine content: 0.3%
The balanced rheology of Restylane Kysse allows smooth extrusion, precise control, and natural integration - ideal for creating soft, kissable lips and youthful definition.
Injection depth & tools
Recommended depth: Superficial to mid-dermis / submucosal plane (lips)
Injection techniques: Linear threading, micro-bolus, or tenting technique
Recommended instruments: 30G needle or 27G cannula
Always inject slowly under aseptic conditions. Aspirate before each injection to minimize the risk of intravascular complications.
Storage & handling
Store at 2 °C - 25 °C in a dry, shaded place
Do not freeze or expose to direct sunlight
Single-use only - use immediately after opening
Dispose of needles and syringes according to local medical waste regulation
Juvederm Ultra 2 - for subtle lip hydration and natural rejuvenation
For use by licensed medical professionals only. Not intended for self-injection.
Patients should avoid alcohol for at least 24 hours before and after treatment to minimize vasodilation, bruising, and swelling.
Contraindicated during pregnancy. There are no adequate controlled studies evaluating filler safety in pregnant patients; elective procedures should be postponed until after delivery.
Not recommended while breastfeeding due to insufficient data on HA metabolite excretion in breast milk. Treatment should be deferred until the completion of the breastfeeding period.
Inject small aliquots into the superficial to mid-dermis or submucosal layer of the lips using linear threading, serial puncture, or fanning technique. Adjust injection depth and volume according to the patient’s anatomy and desired correction. Always aspirate prior to injection, proceed slowly, and avoid intravascular placement. Maintain aseptic technique throughout the procedure.
Common post-treatment reactions include mild redness, swelling, tenderness, or bruising at the injection site, typically resolving within several days. Rare but serious complications such as vascular occlusion, blanching, severe pain, or visual disturbances require immediate medical attention. Cold compresses and avoiding pressure or heat for 24–48 hours may help reduce localized reactions.
Cross-linked hyaluronic acid binds and retains water molecules, restoring hydration and volume to the lips and surrounding tissue. The Optimal Balance Technology™ ensures a balanced viscosity and elasticity profile, enabling seamless tissue integration and natural-looking flexibility during facial expression. Over time, the gel biodegrades completely, leaving improved lip texture and suppleness.
Cross-linked Hyaluronic Acid (20 mg/ml) and Lidocaine (0.3%) for patient comfort and procedural ease. Non-animal stabilized HA designed for precision shaping, flexibility, and natural tissue harmony.
